Analytical Data
-
Gene name
TRAPPC3
- Application
-
Alternative Names
TRAPPC3；BET3；Trafficking Protein particle complex subunit 3
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O43617
-
Expression Region
1-180aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MSRQANRGTE SKKMSSELFT LTYGALVTQL CKDYENDEDV NKQLDKMGFN IGVRLIEDFL ARSNVGRCHD FRETADVIAK VAFKMYLGIT PSITNWSPAG DEFSLILENN PLVDFVELPD NHSSLIYSNL LCGVLRGALE MVQMAVEAKF VQDTLKGDGV TEIRMRFIRR IEDNLPAGEE
-
Molecular Weight
22 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRAPPC3 (Transport Protein Particle Complex 3) is a critical component of the TRAPP (Transport Protein Particle) complex, which plays a pivotal role in the intracellular trafficking of proteins and lipids. Research has increasingly focused on TRAPPC3 due to its implications in several cellular processes, including autophagy, secretion, and maintenance of cellular homeostasis. Mutations in the TRAPPC3 gene have been linked to developmental disorders, particularly in the context of intellectual disability and growth abnormalities. Understanding the structure and function of TRAPPC3 is essential for elucidating its role in these conditions. Recent studies have employed recombinant protein techniques to generate TRAPPC3, enabling detailed investigations into its biochemical properties, interactions with other TRAPP subunits, and the functional consequences of pathogenic mutations. By studying the recombinant TRAPPC3 protein, researchers aim to uncover the mechanistic pathways underlying its involvement in cellular transport processes and to explore potential therapeutic targets for related disorders. The continued exploration of TRAPPC3 not only deepens our understanding of cellular dynamics but also opens avenues for novel interventions in genetic diseases associated with TRAPPC3 dysfunction.
