Analytical Data
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Gene name
NXPH4
- Application
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Alternative Names
NXPH4；NPH4；Neurexophilin-4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95158
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Expression Region
24-308aa
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AA Sequence
QIPESGR PQYLGLRPAA AGAGAPGQQL PEPRSSDGLG VGRAWSWAWP TNHTGALARA GAAGALPAQR TKRKPSIKAA RAKKIFGWGD FYFRVHTLKF SLLVTGKIVD HVNGTFSVYF RHNSSSLGNL SVSIVPPSKR VEFGGVWLPG PVPHPLQSTL ALEGVLPGLG PPLGMAAAAA GPGLGGSLGG ALAGPLGGAL GVPGAKESRA FNCHVEYEKT NRARKHRPCL YDPSQVCFTE HTQSQAAWLC AKPFKVICIF VSFLSFDYKL VQKVCPDYNF QSEHPYFG
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Molecular Weight
33 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NXPH4, or Neurexophilin 4, is a member of the neurexophilin family, which is known for its role in synaptic function and neuron-glia interactions. Researchers have been increasingly interested in NXPH4 due to its potential involvement in neurodevelopmental processes and neurological disorders. The protein is characterized by its ability to modulate synaptic transmission through interactions with presynaptic adhesion molecules and neuropeptides, suggesting a crucial regulatory role at synapses. Emerging studies indicate that alterations in NXPH4 expression or function may be linked to conditions such as autism spectrum disorders and schizophrenia, underscoring the importance of understanding its molecular mechanisms. Additionally, NXPH4's interactions with the neuroligin family of proteins highlight its potential in mediating excitatory and inhibitory synaptic connections. Given the rising concerns regarding mental health and neurodevelopmental disorders, the research on NXPH4 recombinant protein is vital for uncovering its biological functions and potential therapeutic implications, paving the way for targeted treatments that could ameliorate synaptic dysfunctions associated with these conditions. As scientists strive to delineate its role within the broader neurobiological landscape, NXPH4 represents a promising target for future investigations aimed at understanding complex neural networks and developing effective interventions for related disorders.
