Analytical Data
-
基因名
TPST1
- Application
-
别名
TPST1；Protein-tyrosine sulfotransferase 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O60507
-
表达区间
26-370aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH TGSMQHAMEC HHRIEERSQP VKLESTRTTV RTGLDLKANK TFAYHKDMPL IFIGGVPRSG TTLMRAMLDA HPDIRCGEET RVIPRILALK QMWSRSSKEK IRLDEAGVTD EVLDSAMQAF LLEIIVKHGE PAPYLCNKDP FALKSLTYLS RLFPNAKFLL MVRDGRASVH SMISRKVTIA GFDLNSYRDC LTKWNRAIET MYNQCMEVGY KKCMLVHYEQ LVLHPERWMR TLLKFLQIPW NHSVLHHEEM IGKAGGVSLS KVERSTDQVI KPVNVGALSK WVGKIPPDVL QDMAVIAPML AKLGYDPYAN PPNYGKPDPK IIENTRRVYK GEFQLPDFLK EKPQTEQVE
-
分子量
42 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TPST1 (tyrosyl-protein sulfotransferase 1) is an important enzyme involved in the post-translational modification of proteins through the addition of sulfate groups to tyrosine residues, a process known as sulfation. This modification plays a critical role in various biological processes, including cell signaling, protein stability, and interactions between proteins and other biomolecules. Dysregulation of TPST1 has been implicated in several diseases, including cancer and cardiovascular disorders, making it a significant target for therapeutic research. Understanding the structure and function of TPST1 can help elucidate its role in cellular mechanisms and disease pathology. Furthermore, the production of recombinant TPST1 protein is essential for studying its biochemical characteristics, enzyme kinetics, and potential inhibitors. Researchers utilize advanced techniques in molecular biology and protein chemistry to produce and characterize TPST1, aiming to uncover its regulatory mechanisms and explore its potential as a biomarker or therapeutic target. As such, studies on TPST1 not only contribute to the fundamental understanding of sulfation processes in the cell but also pave the way for the development of novel therapeutic strategies in treating related diseases.
