Analytical Data
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Gene name
TOMM34
- Application
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Alternative Names
TOMM34；URCC3；Mitochondrial import receptor subunit TOM34
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15785
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Expression Region
1-309aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAPKFPD SVEELRAAGN ESFRNGQYAE ASALYGRALR VLQAQGSSDP EEESVLYSNR AACHLKDGNC RDCIKDCTSA LALVPFSIKP LLRRASAYEA LEKYPMAYVD YKTVLQIDDN VTSAVEGINR MTRALMDSLG PEWRLKLPSI PLVPVSAQKR WNSLPSENHK EMAKSKSKET TATKNRVPSA GDVEKARVLK EEGNELVKKG NHKKAIEKYS ESLLCSNLES ATYSNRALCY LVLKQYTEAV KDCTEALKLD GKNVKAFYRR AQAHKALKDY KSSFADISNL LQIEPRNGPA QKLRQEVKQN LHKDCTEALKLD GKNVKAFYRR AQAHKALKDY KSSFADISNL LQIEPRNGPA QKLRQEVKQN LH
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Molecular Weight
37 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TOMM34 (Translocase of Outer Mitochondrial Membrane 34) is a mitochondrial protein that plays a significant role in the import and processing of nuclear-encoded proteins into mitochondria. The proper functioning of TOMM34 is essential for maintaining mitochondrial integrity, bioenergetics, and overall cellular health. Recent research highlights its potential involvement in various cellular processes, including apoptosis, oxidative stress response, and neurodegenerative diseases. Dysfunction in TOMM34 has been implicated in the pathogenesis of conditions such as Alzheimer's disease and Parkinson's disease, making it a target of considerable interest in biomedical research. The production of recombinant TOMM34 protein allows for in-depth studies of its structure, function, and interaction with other mitochondrial proteins, providing insights into its role in mitochondrial dynamics and disease mechanisms. Investigating TOMM34 through recombinant technology could facilitate the development of therapeutic strategies aimed at modulating its activity and addressing mitochondrial-related disorders, thus emphasizing the importance of this protein in both basic and applied research in mitochondrial biology.
