Cat: PA2000-5551

Recombinant Human APRIN Protein,GST

  • Price
  • Size
  • Number

    Order now. For delivery time, please consult customer service

  • Pre-sale guidance and worry-free after-sale service
  • Quality assurance for cold chain transportation

Analytical Data

  • Gene name

    APRIN

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PDS5B; APRIN; AS3; KIAA0979; Sister chromatid cohesion Protein PDS5 homolog B; Androgen-induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff-associated Protein AS3

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NTI5

  • Expression Region

    1168- 1259aa

  • AA Sequence

    GRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASES

  • Molecular Weight

    35.86 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

Related Products

Protein Description

APRIN (APC-C1-2-related protein) is a recently identified protein that has gained attention in the field of cellular biology due to its potential roles in cell cycle regulation and genomic stability. Research into APRIN's structure and function has revealed its involvement in the regulation of the anaphase-promoting complex/cyclosome (APC/C), a crucial E3 ubiquitin ligase that governs the transition from metaphase to anaphase during cell division. Aberrant regulation of the APC/C has been linked to various cancers and other diseases, making APRIN a significant target for understanding the mechanisms of tumorigenesis. Furthermore, studies utilizing recombinant APRIN protein have shed light on its mechanisms of action, potential interactions with other cell cycle regulators, and its role in DNA damage response pathways. Understanding the precise function and regulation of APRIN could pave the way for the development of novel therapeutic strategies aimed at manipulating the cell cycle in cancer treatment and improving genomic integrity in a range of biological contexts. These insights position APRIN as a valuable subject of study, with implications extending beyond basic biology into clinical applications.

E-mail

sales@ipodix.com

Sales

+1 2092920560


Contact us via WhatsApp

IPODIX Biotech Inc

2108 N ST, STE N
Sacramento, CA 95816, USA

For Product Information and Orders

sales@ipodix.com

For Business Collaboration

sales@ipodix.com

For CRO Services

sales@ipodix.com

For Technical Support

sales@ipodix.com
  • 50000+

    Recombinant Proteins

  • 100+

    Researchers

  • 100+

    Countries Served

  • ISO

    Certified Quality

Committed to Quality
Driven by Innovation

Learn More About US