Analytical Data
-
Gene name
APOL3
- Application
-
Alternative Names
ApoL III; ApoL-III; APOL3; APOL3_HUMAN; APOLIII; ApolipoProtein L 3; ApolipoProtein L III; ApolipoProtein L-III; ApolipoProtein L3; ApolipoProtein LIII; CG12 1; CG12_1; CG121; TNF inducible Protein CG12 1; TNF-inducible Protein CG12-1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O95236
-
Expression Region
1-402aa
-
AA Sequence
MGLGQGWGWE ASCFACLIRS CCQVVTFTFP FGFQGISQSL ENVSGYYADA RLEVGSTQLR TAGSCSHSFK RSFLEKKRFT EEATKYFRER VSPVHLQILL TNNEAWKRFV TAAELPRDEA DALYEALKKL RTYAAIEDEY VQQKDEQFRE WFLKEFPQVK RKIQESIEKL RALANGIEEV HRGCTISNVV SSSTGAASGI MSLAGLVLAP FTAGTSLALT AAGVGLGAAS AVTGITTSIV EHSYTSSAEA EASRLTATSI DRLKVFKEVM RDITPNLLSL LNNYYEATQT IGSEIRAIRQ ARARARLPVT TWRISAGSGG QAERTIAGTT RAVSRGARIL SATTSGIFLA LDVVNLVYES KHLHEGAKSA SAEELRRQAQ ELEENLMELT QIYQRLNPCH TH
-
Molecular Weight
44.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
APOL3, or Apolipoprotein L3, is a member of the apolipoprotein family that has garnered research interest due to its role in lipid metabolism and immune response. Originally identified for its association with high-density lipoprotein (HDL) particles, APOL3 has shown potential implications in various physiological and pathological processes, including cardiovascular diseases and metabolic disorders. Its unique structure contains several functional domains that may facilitate interactions with other lipoproteins and cellular receptors, impacting lipid transport and cellular signaling pathways. Recent studies have also indicated that APOL3 may play a role in modulating inflammatory responses and protecting against certain infections, highlighting its potential as a therapeutic target. However, the precise mechanisms underlying APOL3's functions remain poorly understood, necessitating further investigation. The development of recombinant APOL3 proteins through biotechnology offers a promising avenue for elucidating these mechanisms, enabling scientists to explore its interactions, functional properties, and potential applications in clinical settings. By producing and characterizing APOL3 in a controlled environment, researchers can study its involvement in lipid metabolism and immune modulation, ultimately contributing to a deeper understanding of its biological significance and potential role in disease treatment.
