Analytical Data
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基因名
OSBPL1A
- Application
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别名
FLJ10217; ORP 1; ORP-1; ORP1; OSBL1_HUMAN; OSBP 8; OSBP L1; OSBP related protein 1; OSBP-related protein 1; OSBP8; OSBPL 1; OSBPL 1A; OSBPL 1B; OSBPL1; OSBPL1A; OSBPL1B; Oxysterol binding protein like 1A; Oxysterol binding protein like 1B; Oxysterol binding protein related protein 1; Oxysterol-binding protein-related protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BXW6
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表达区间
1-100 aa
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氨基酸序列
MNTEAEQQLLHHARNGNAEEVRQLLETMARNEVIADINCKGRSKSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDMRDTPLHRAAFTGRKICSQGS
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分子量
37.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OSBPL1A, or Oxysterol-binding protein-like 1A, is a member of the oxysterol-binding protein family, which plays a crucial role in lipid metabolism and cellular signaling. Recent studies have indicated that OSBPL1A is involved in regulating cholesterol homeostasis and has implications in various physiological processes, including cellular proliferation and apoptosis. Given its association with lipid transport and signaling, abnormalities in OSBPL1A expression or function have been linked to several pathological conditions, including metabolic disorders and cardiovascular diseases. Moreover, the protein's structure suggests that it may interact with phospholipids and sterols, influencing membrane dynamics and cellular responses to environmental changes. As such, producing recombinant OSBPL1A has become essential for in-depth functional studies, allowing researchers to investigate its specific roles within the cell and its potential as a therapeutic target. Understanding the biochemical pathways involving OSBPL1A can not only provide insights into the fundamental aspects of cell biology but also open new avenues for treating diseases associated with lipid imbalances. There is an increasing interest in developing OSBPL1A as a biomarker for disease progression in metabolic syndromes, making the study of its recombinant protein increasingly relevant in the field of biomedical research.
