Analytical Data
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Gene name
SUMO3
- Application
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Alternative Names
SUMO3；SMT3A；Small ubiquitin-related modifier 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P55854
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Expression Region
1-92aa
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AA Sequence
MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SUMO3 (Small Ubiquitin-like Modifier 3) is a member of the SUMO protein family, which plays a crucial role in post-translational modification processes known as SUMOylation. This modification involves the conjugation of SUMO proteins to target substrates, influencing various cellular functions such as nuclear transport, transcriptional regulation, and DNA repair. Research has shown that SUMO3 is particularly important in stress responses and cell survival, as it can modify protein interactions and stability under various physiological conditions. Dysregulation of SUMOylation pathways has been implicated in several diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Consequently, understanding the molecular mechanisms and interactions involving SUMO3 is of great significance. Recent studies have focused on elucidating the structure-function relationship of SUMO3 and its conjugated substrates, aiming to uncover potential therapeutic targets for diseases associated with SUMOylation dysregulation. This research highlights the need for comprehensive studies on SUMO3 to unravel its functional roles and regulatory mechanisms, paving the way for novel biomedical applications and interventions in SUMO-related pathologies.
