Analytical Data
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Gene name
SNRPE
- Application
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Alternative Names
SNRPE;Small nuclear ribonucleoProtein E
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P62304
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Expression Region
1-92aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MAYRGQGQKV QKVMVQPINL IFRYLQNRSR IQVWLYEQVN MRIEGCIIGF DEYMNLVLDD AEEIHSKTKS RKQLGRIMLK GDNITLLQSV SN
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Molecular Weight
13 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNRPE (Small Nuclear Ribonucleoprotein U5 Subunit E) is a key component of the spliceosome, the complex responsible for the removal of introns from pre-mRNA during the process of gene expression. The study of SNRPE and its role in spliceosome assembly and function has gained significant attention due to its implications in RNA processing and gene regulation. Recent research highlights the importance of SNRPE in maintaining the integrity of mRNA splicing, which is critical for proper gene expression and cellular function. Dysregulation of splicing mechanisms, to which SNRPE contributes, has been associated with various diseases, including cancer and neurodegenerative disorders. Investigating the structural and functional properties of recombinant SNRPE proteins provides insights into the molecular mechanisms underlying splicing and potential therapeutic targets. Additionally, advancements in recombinant protein technology enable the production of SNRPE variants for functional assays, allowing researchers to explore its interactions with other spliceosomal proteins and RNA elements. Overall, SNRPE serves as a vital focus for researchers aiming to elucidate the complexities of RNA splicing and its broader implications in health and disease.
