Cat: PA2000-1264

Recombinant Human RHOM2 Protein,His

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Analytical Data

  • Gene name

    RHOM2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RHOM2;RBTN2;RBTNL1;RHOM2;Rhombotin-2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P25791

  • Expression Region

    1-158aa

  • AA Sequence

    MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYW HEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRPFGQDGLCASCDKR IRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYE WTKINGMI

  • Molecular Weight

    43 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

RHOM2 (Rho Family GTPase 2) is a member of the Rho family of GTPases, which play crucial roles in various cellular processes, including cell proliferation, differentiation, and cytoskeletal dynamics. Research into RHOM2 has gained momentum due to its involvement in signal transduction pathways and its potential implications in diseases, particularly cancer and cardiovascular conditions. Studies have shown that RHOM2 can influence cell migration and invasion, which are critical factors in tumor metastasis. Additionally, RHOM2 participates in the regulation of inflammation and immune responses, indicating its broader relevance in physiological and pathological contexts. Given its multifunctional nature, RHOM2 presents an intriguing target for therapeutic intervention. The development of recombinant RHOM2 proteins enables detailed exploration of its biochemical properties, facilitating investigations into its structural dynamics and interactions with other cellular proteins. Understanding the molecular mechanisms by which RHOM2 exerts its effects can provide insights into its role in health and disease, making it a significant focus for future research endeavors in cell biology and therapeutic development.

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