Analytical Data
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Gene name
ACTG1
- Application
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Alternative Names
ACT ; ACTB ; ACTG ; ACTG_HUMAN; actg1; Actin; Actin; cytoplasmic 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P63261
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Expression Region
1-375aa
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AA Sequence
MEEEIAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF
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Molecular Weight
41.7 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACTG1, the gene encoding cytoplasmic actin gamma, plays a crucial role in various cellular processes, including cytoskeletal dynamics, cell motility, and intracellular transport. It is ubiquitously expressed and is particularly vital for maintaining the structural integrity of cells in different tissues. Dysregulation of ACTG1 is linked to several pathologies, including deafness and other developmental disorders, highlighting its importance in both normal physiology and disease. Researchers have focused on characterizing ACTG1 through recombinant protein studies to better understand its structure, function, and interactions with other cellular components. These studies aim to elucidate the mechanisms underlying ACTG1's role in cellular architecture and disease pathology, paving the way for potential therapeutic strategies. Given its central role in cellular mechanics, understanding ACTG1 through recombinant protein expression offers insights into actin filament dynamics and provides opportunities for investigating targeted treatments for conditions associated with its dysfunction.
