Analytical Data
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基因名
ACTC
- Application
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别名
ACTC; ACTC_HUMAN; ACTC1; Actin alpha cardiac muscle 1; Actin; alpha cardiac muscle 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P68032
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表达区间
3-377aa
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氨基酸序列
DDEETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP EEHPTLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VTHNVPIYEG YALPHAIMRL DLAGRDLTDY LMKILTERGY SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK SYELPDGQVI TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS LSTFQQMWIS KQEYDEAGPS IVHRKCF
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分子量
42 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of ACTC recombinant proteins has gained significant attention due to their potential applications in understanding muscle physiology and pathology. Alpha-cardiac actin (ACTC) is a crucial structural protein found in cardiac and skeletal muscle, playing a vital role in muscle contraction and maintenance of the cytoskeleton. Mutations in the ACTC gene have been linked to various cardiac diseases, particularly familial hypertrophic cardiomyopathy (HCM), making this protein an important target for research. Recombinant expression of ACTC allows researchers to produce large quantities of the protein for functional studies, structural analysis, and therapeutic development. By investigating the biochemical properties and interactions of ACTC, scientists aim to elucidate the mechanisms underlying muscle function and related disorders. Moreover, the availability of recombinant ACTC facilitates the exploration of potential pharmacological interventions and the design of biomarkers for early diagnosis of related diseases. Thus, the research on ACTC recombinant proteins not only enhances our understanding of muscle biology but also paves the way for innovative strategies in the treatment of muscular and cardiovascular conditions.
