Analytical Data
-
基因名
SEPT2
- Application
-
别名
SEPTIN2;DIFF6;KIAA0158;NEDD5;Septin-2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q15019
-
表达区间
1-361aa
-
氨基酸序列
MSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGHHV
-
分子量
57.5kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SEPT2 (Septin 2) is a member of the septin family of GTP-binding proteins, which play a crucial role in various cellular processes, including cytoskeletal organization, cell division, and the formation of membranous structures. The study of SEPT2 has gained traction due to its involvement in essential cellular functions and its potential implications in human diseases, such as cancer and neurodegenerative disorders. SEPT2 is known to form hetero-oligomeric complexes with other septins, contributing to the integrity and functionality of cellular frameworks. Abnormalities in septin expression and function have been associated with disrupted cell signaling pathways, leading to abnormal cell proliferation and migration. Additionally, SEPT2's role in the formation of septin-based structures, such as midbody and ring-like formations during cytokinesis, highlights its importance in ensuring proper cell division. Recent research efforts have focused on elucidating the structural dynamics of SEPT2, its interaction with other proteins, and its regulatory mechanisms within the cell. Understanding these aspects could provide insights into the molecular underpinnings of associated diseases and offer potential avenues for therapeutic interventions. Therefore, the study of SEPT2 and its recombinant protein forms is pivotal in advancing our comprehension of cell biology and developing strategies to target septin-related pathologies.
