Analytical Data
-
Gene name
DCDC1
- Application
-
Alternative Names
DCDC1；DCDC5；KIAA1493；Doublecortin domain-containing Protein 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P59894
-
Expression Region
1-354aa
-
AA Sequence
MAKTGAEDHR EALSQSSLSL LTEAMEVLQQ SSPEGTLDGN TVNPIYKYIL NDLPREFMSS QAKAVIKTTD DYLQSQFGPN RLVHSAAVSE GSGLQDCSTH QTASDHSHDE ISDLDSYKSN SKNNSCSISA SKRNRPVSAP VGQLRVAEFS SLKFQSARNW QKLSQRHKLQ PRVIKVTAYK NGSRTVFARV TVPTITLLLE ECTEKLNLNM AARRVFLADG KEALEPEDIP HEADVYVSTG EPFLNPFKKI KDHLLLIKKV TWTMNGLMLP TDIKRRKTKP VLSIRMKKLT ERTSVRILFF KNGMGQDGHE ITVGKETMKK VLDTCTIRMN LNLPARYFYD LYGRKIEDIS KGKH
-
Molecular Weight
200.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCDC1, or doublecortin domain containing 1, is a gene that encodes a protein involved in neuronal development and function. Research into DCDC1 has gained traction due to its potential implications in various neurological conditions and its role in neuronal migration and differentiation. Mutations or dysregulation of DCDC1 have been linked to developmental disorders, particularly affecting the cerebral cortex. The protein's structure features doublecortin motifs, which are crucial for microtubule stabilization, signaling pathways, and cytoskeletal organization during neuronal development. Investigations into DCDC1 protein expression, localization, and function are critical for understanding its role in neurogenesis and its potential impact on neurodevelopmental disorders such as lissencephaly and schizophrenia. As researchers explore DCDC1 in detail, including its interactions with other proteins and its functional dynamics, new therapeutic approaches may emerge for conditions characterized by disruptions in neural development. The ongoing studies aim to unravel the molecular pathways associated with DCDC1, paving the way for targeted interventions and a deeper understanding of the complex mechanisms governing brain development and related disorders.
