Analytical Data
-
Gene name
ENOX1
- Application
-
Alternative Names
ENOX1；Ecto-NOX disulfide-thiol exchanger 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8TC92
-
Expression Region
1-643aa
-
AA Sequence
MVDAGGVENITQLPQELPQMMAAAADGLGSIAIDTTQLNMSVTDPTAWAT AMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGLGLV PPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLP ENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRM RLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRL RPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSA NQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIV AVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEM EMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELL KQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQ AKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDSNEINVLTVALVNQD RENNIEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSK ISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT
-
Molecular Weight
77 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENOX1, or ENOX1 protein, is a putative oncogene that encodes an enzyme involved in the production of reactive oxygen species (ROS) at the plasma membrane, playing significant roles in cell signaling, proliferation, and differentiation. Its dysregulation has been associated with various cancers, making it a potential biomarker for tumor progression and a target for therapeutic interventions. Research has revealed that ENOX1 is overexpressed in several types of malignancies, including breast, prostate, and lung cancers. As a part of the NADH oxidase family, ENOX1 is believed to contribute to the tumor microenvironment by enhancing cellular survival and promoting aggressive phenotypes. The study of recombinant ENOX1 protein offers insights into its biochemical properties and functions, providing a platform for understanding its role in tumor biology and the development of novel anticancer strategies. By characterizing ENOX1 in vitro, researchers aim to elucidate its enzymatic mechanisms and interactions with other cellular components, which could lead to new diagnostic markers and therapeutic targets in cancer treatment. The development of stable ENOX1 recombinant proteins is crucial for facilitating these studies, enabling researchers to explore the potential of ENOX1 as a therapeutic target and its implications in cancer metabolism.
