Analytical Data
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基因名
ENOX1
- Application
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别名
ENOX1；Ecto-NOX disulfide-thiol exchanger 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TC92
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表达区间
1-643aa
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氨基酸序列
MVDAGGVENITQLPQELPQMMAAAADGLGSIAIDTTQLNMSVTDPTAWAT AMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGLGLV PPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLP ENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRM RLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRL RPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSA NQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIV AVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEM EMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELL KQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQ AKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDSNEINVLTVALVNQD RENNIEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSK ISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT
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分子量
77 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ENOX1, or ENOX1 protein, is a putative oncogene that encodes an enzyme involved in the production of reactive oxygen species (ROS) at the plasma membrane, playing significant roles in cell signaling, proliferation, and differentiation. Its dysregulation has been associated with various cancers, making it a potential biomarker for tumor progression and a target for therapeutic interventions. Research has revealed that ENOX1 is overexpressed in several types of malignancies, including breast, prostate, and lung cancers. As a part of the NADH oxidase family, ENOX1 is believed to contribute to the tumor microenvironment by enhancing cellular survival and promoting aggressive phenotypes. The study of recombinant ENOX1 protein offers insights into its biochemical properties and functions, providing a platform for understanding its role in tumor biology and the development of novel anticancer strategies. By characterizing ENOX1 in vitro, researchers aim to elucidate its enzymatic mechanisms and interactions with other cellular components, which could lead to new diagnostic markers and therapeutic targets in cancer treatment. The development of stable ENOX1 recombinant proteins is crucial for facilitating these studies, enabling researchers to explore the potential of ENOX1 as a therapeutic target and its implications in cancer metabolism.
