Analytical Data
-
Gene name
NIPSNAP3B
- Application
-
Alternative Names
Nipsnap homolog 3B (C. elegans); NIPSNAP3; NipSnap3B; NPS3B_HUMAN; OTTHUMP00000021829 ; Protein NipSnap homolog 3B; SNAP1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BS92
-
Expression Region
1-247 aa
-
AA Sequence
MLVLRSGLTK ALASRTLAPQ VCSSFATGPR QYDGTFYEFR TYYLKPSNMN AFMENLKKNI HLRTSYSELV GFWSVEFGGR TNKVFHIWKY DNFAHRAEVR KALANCKEWQ EQSIIPNLAR IDKQETEITY LIPWSKLEKP PKEGVYELAV FQMKPGGPAL WGDAFERAIN AHVNLGYTKV VGVFHTEYGE LNRVHVLWWN ESADSRAAGR HKSHEDPRVV AAVRESVNYL VSQQNMLLIP ASFSPLK
-
Molecular Weight
28.3 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NIPSNAP3B is a member of the NIPSNAP protein family, which has garnered interest due to its potential roles in cellular processes and disease mechanisms. This protein is implicated in mitochondrial dynamics, influencing mitochondrial morphology and function, which are critical for energy metabolism and cellular health. Recent studies have suggested that NIPSNAP3B may be involved in neurodegenerative diseases, highlighting its significance in neuronal health and the maintenance of synaptic function. The research on NIPSNAP3B is particularly focused on its structural properties and how mutations or dysregulation can contribute to various pathologies. Given the increasing prevalence of mitochondrial dysfunction in numerous disorders, understanding the functional implications of NIPSNAP3B through recombinant protein studies can provide insights into potential therapeutic targets. Through the development of recombinant NIPSNAP3B, researchers aim to elucidate its biochemical properties, interactions, and functions in cellular contexts. This investigation not only contributes to the basic understanding of mitochondrial biology but also opens avenues for exploring NIPSNAP3B as a novel biomarker or therapeutic target in neurodegenerative diseases and other conditions linked to mitochondrial dysfunction.
