Analytical Data
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基因名
RTCA
- Application
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别名
RTCA;RPC;RPC1;RTC1;RNA 3'-terminal phosphate cyclase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00442
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表达区间
1-366aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMAGPRVEVDGSIMEGGGQILRVSTALS CLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGSTEI TFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGTNA EMAPQIDYTVMVFKPIVEKFGFIFNCDIKTRGYYPKGGGEVIVRMSPVKQ LNPINLTERGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYV NIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEA AEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPVTLHTQTAIHF AEQIAKAKFIVKKSEDEEDAAKDTYIIECQGIGMTNPNL
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RTCA (Regulatory T Cell Antigen) is a protein that plays a pivotal role in the immune system, particularly in the function and development of regulatory T cells (Tregs). Tregs are crucial for maintaining immune homeostasis and preventing autoimmunity by modulating the activity of other immune cells. Research into RTCA has gained importance due to its potential implications in autoimmune diseases, cancer immunotherapy, and transplantation. Understanding the mechanisms by which RTCA influences Treg function could uncover new therapeutic targets for enhancing immune tolerance and developing effective treatments. Furthermore, the ability to produce recombinant RTCA protein offers the opportunity to study its structure-function relationship and interactions with other immune molecules. As the field of immunology continues to evolve, investigating the role of RTCA and its potential as a biomarker or therapeutic agent represents a promising avenue for future research, aiming to elucidate the complexities of immune regulation and pave the way for novel interventions in immune-related disorders.
