Analytical Data
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基因名
RPS20
- Application
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别名
RPS20;Small ribosomal subunit Protein uS10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P60866
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表达区间
1-142aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAFKDTG KTPVEPEVAI HRIRITLTSR NVKSLEKVCA DLIRGAKEKN LKVKGPVRMP TKTLRITTRK TPCGEGSKTW DRFQMRIHKR LIDLHSPSEI VKQITSISIE PGVELIESTD AEPMDTEGQQ YTLRSVFESP GTCPF
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分子量
18 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RPS20, a ribosomal protein belonging to the 40S subunit, plays a critical role in ribosome biogenesis and protein synthesis. Research into RPS20 has gained significance due to its involvement in various cellular processes and its potential links to human diseases, including cancer and genetic disorders. Deficiencies or mutations in ribosomal proteins like RPS20 can result in ribosomopathies, which are syndromes characterized by inherited bone marrow failure and predisposition to cancers. Given RPS20's essential role in the assembly and function of ribosomes, studies have focused on its structure, function, and regulation. Techniques such as X-ray crystallography and cryo-electron microscopy have provided insights into the molecular architecture of RPS20 and its interactions with rRNA and other ribosomal proteins. Additionally, investigations into post-translational modifications and the impact of RPS20 dysregulation on translation efficiency have further illuminated its significance in cellular physiology. As research continues, understanding RPS20's role in ribosome function may unveil new therapeutic targets for diseases associated with ribosomal dysfunction, thereby enhancing our knowledge of cell biology and advancing potential medical interventions.












