Analytical Data
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基因名
KLHDC2
- Application
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别名
KLHDC2;HCA33;Kelch domain-containing Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2U9
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表达区间
1-406aa
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氨基酸序列
MADGNEDLRADDLPGPAFESYESMELACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCANNLLVHHRAAHSNEILIFSVQPKSLVRLSLEAVICFKEMLANSWNCLPKHLLHSVNQRFGSNNTSGS
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分子量
46.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLHDC2, or Kelch domain-containing protein 2, is a member of the Kelch-like protein family known for its role in various cellular processes, including signal transduction and protein ubiquitination. Research has highlighted KLHDC2's potential involvement in critical biological functions, such as developmental regulation and immune response modulation. Emerging studies suggest that this protein may play a significant role in cancer biology, particularly in tumor progression and metastasis, indicating its potential as a therapeutic target. Given the complexities of its interactions and functionalities, scientists have focused on elucidating the structural characteristics and mechanisms of KLHDC2 through recombinant protein studies. By producing KLHDC2 in a laboratory setting, researchers aim to better understand its biochemical properties and interactions with other cellular components, thereby laying the groundwork for potential applications in disease treatment and biomarker development. These investigations not only enhance our knowledge of KLHDC2's biological roles but could pave the way for innovative strategies in clinical interventions. As such, KLHDC2 represents a promising avenue for further research in protein biology and its implications in health and disease.












