Analytical Data
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Gene name
LYPLA3
- Application
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Alternative Names
LYPLA3；LYPLA3；Lysosomal phospholipase A and acyltransferase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NCC3
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Expression Region
34-412aa
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AA Sequence
AGRHPPV VLVPGDLGNQ LEAKLDKPTV VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP
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Molecular Weight
46.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LYPLA3 (lysophospholipase I) is an important enzyme involved in lipid metabolism, particularly in the hydrolysis of lysophospholipids. Its role in cellular signaling and membrane dynamics has drawn significant attention in recent years, especially due to its association with various diseases, including cancer and metabolic disorders. Research has shown that LYPLA3 may influence cell growth, differentiation, and apoptosis through its enzymatic activity and interactions with other cellular pathways. The recombinant protein has been studied to elucidate its structural characteristics and functional roles in lipid metabolism. Advances in recombinant DNA technology have made it possible to produce LYPLA3 at scale for both in vitro and in vivo studies, facilitating the investigation of its pharmacological potential. Understanding LYPLA3's mechanisms of action not only enhances our knowledge of lipid biology but also opens up new avenues for therapeutic interventions targeting related pathologies. Thus, LYPLA3 recombinant protein serves as a valuable tool for researchers aiming to dissect the intricacies of lipid signaling and its implications in health and disease.
