Analytical Data
-
基因名
SRPR
- Application
-
别名
SRPR；SRPR；Signal recognition particle receptor subunit alpha
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P08240
-
表达区间
1-638aa
-
氨基酸序列
MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHE ALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQ QSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVR SMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPEN GVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWEL GGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLI AKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQ RRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVL IAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAG IAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFV GEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA
-
分子量
96 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SRPR (Signal Recognition Particle Receptor) is a crucial component in the cellular protein translocation process, specifically in the pathway responsible for directing nascent proteins to the endoplasmic reticulum (ER) for proper folding and modification. The research surrounding SRPR primarily focuses on its role in signal recognition, interacting with the signal recognition particle (SRP) to facilitate the transport of secretory and membrane proteins. Recent studies have highlighted the importance of SRPR in various biological processes and its implication in diseases, making it a significant target for potential therapeutic interventions. Given its essential function in protein synthesis and translocation, understanding the structural and functional dynamics of SRPR is critical. Furthermore, the manipulation of SRPR through recombinant technology enables scientists to explore its properties in detail, paving the way for developing novel strategies in biotechnology and medicine. The investigation of SRPR and its associated pathways offers insights into fundamental cellular mechanisms and underscores the importance of protein homeostasis in health and disease.
