Analytical Data
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基因名
KLC3
- Application
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别名
KLC3；KLC2；KLC2L；Kinesin light chain 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P597
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表达区间
1-504aa
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氨基酸序列
MSVQVAAPGSAGLGPERLSPEELVRQTRQVVQGLEALRAEHHGLAGHLAEALAGQGPAAGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEESVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEAAAGAAGMKRAMSLNTLNVDAPRAPGTQFPSWHLDKAPRTLSASTQDLSPH
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分子量
57.4kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLC3, or kinesin light chain 3, is a critical component of the kinesin motor protein family, which plays a pivotal role in intracellular transport processes by facilitating the movement of cargo along microtubules. Research into KLC3 has garnered significant attention due to its involvement in various cellular functions, such as neuronal integrity, organelle distribution, and cytokinesis. Notably, KLC3 exhibits a unique expression pattern in various tissues, particularly in the brain, which underscores its potential significance in neurological disorders. Recent studies have suggested that dysregulation of KLC3 may contribute to the pathophysiology of neurodegenerative diseases, making it a target for therapeutic intervention. Furthermore, KLC3's ability to form complexes with different motor proteins enhances its functional versatility, impacting processes like vesicle transport and synaptic function. The recombinant production of KLC3 protein has become a valuable tool for characterizing its biochemical properties, elucidating its role in cellular dynamics, and exploring its interactions with other protein partners. As research progresses, understanding the intricacies of KLC3's functions and its implications in health and disease could pave the way for innovative strategies in treating conditions that stem from impaired intracellular transport mechanisms.
