Analytical Data
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Gene name
NELL1
- Application
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Alternative Names
FLJ45906; IDH3GL; NEL like 1 (chicken); NEL like protein 1; Nel related protein 1; NEL-like 1 (chicken); NEL-like protein 1; Nel-related protein 1; NELL 1 protein short isoform; Nell1; NELL1_HUMAN; Neural epidermal growth factor like 1; NRP1; Protein kinase C binding protein NELL1; Protein kinase C-binding protein NELL1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92832
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Expression Region
22-810 aa
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AA Sequence
FGMDPDLQM DIVTELDLVN TTLGVAQVSG MHNASKAFLF QDIEREIHAA PHVSEKLIQL FRNKSEFTIL ATVQQKPSTS GVILSIRELE HSYFELESSG LRDEIRYHYI HNGKPRTEAL PYRMADGQWH KVALSVSASH LLLHVDCNRI YERVIDPPDT NLPPGINLWL GQRNQKHGLF KGIIQDGKII FMPNGYITQC PNLNHTCPTC SDFLSLVQGI MDLQELLAKM TAKLNYAETR LSQLENCHCE KTCQVSGLLY RDQDSWVDGD HCRNCTCKSG AVECRRMSCP PLNCSPDSLP VHIAGQCCKV CRPKCIYGGK VLAEGQRILT KSCRECRGGV LVKITEMCPP LNCSEKDHIL PENQCCRVCR GHNFCAEGPK CGENSECKNW NTKATCECKS GYISVQGDSA YCEDIDECAA KMHYCHANTV CVNLPGLYRC DCVPGYIRVD DFSCTEHDEC GSGQHNCDEN AICTNTVQGH SCTCKPGYVG NGTICRAFCE EGCRYGGTCV APNKCVCPSG FTGSHCEKDI DECSEGIIEC HNHSRCVNLP GWYHCECRSG FHDDGTYSLS GESCIDIDEC ALRTHTCWND SACINLAGGF DCLCPSGPSC SGDCPHEGGL KHNGQVWTLK EDRCSVCSCK DGKIFCRRTA CDCQNPSADL FCCPECDTRV TSQCLDQNGH KLYRSGDNWT HSCQQCRCLE GEVDCWPLTC PNLSCEYTAI LEGECCPRCV SDPCLADNIT YDIRKTCLDS YGVSRLSGSV WTMAGSPCTT CKCKNGRVCC SVDFECLQNN
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Molecular Weight
89.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NELL1 (Neural Epidermal Growth Factor-Like 1) is a protein that plays a crucial role in various biological processes, including cell proliferation, differentiation, and survival. It was first identified as a secreted protein with homology to the epidermal growth factor (EGF) family, indicating its potential involvement in signaling pathways that regulate cellular behaviors. Research has shown that NELL1 is expressed in various tissues, particularly in neural and epidermal contexts, suggesting its importance in development and tissue regeneration. In recent studies, NELL1 has emerged as a promising candidate for therapeutic applications, particularly in bone regeneration and wound healing, due to its ability to promote osteoblast differentiation and enhance mineralization. Additionally, it has been implicated in certain pathological conditions, including tumors, highlighting its dual role in promoting normal physiological processes and contributing to disease mechanisms. Recombinant NELL1 protein has been produced for various experimental applications, enabling scientists to investigate its functional mechanisms and therapeutic potential systematically. The development of NELL1 recombinant protein is thus a significant step towards understanding its biological roles and exploring its applications in regenerative medicine and oncology.
