Analytical Data
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Gene name
RNMTL1
- Application
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Alternative Names
MRM3;RNMTL1;rRNA methyltransferase 3. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HC36
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Expression Region
1-420aa
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AA Sequence
MAALVRPARFVVRPLLQVVQAWDLDARRWVRALRRSPVKVVFPSGEVVEQKRAPGKQPRKAPSEASAQEQREKQPLEESASRAPSTWEESGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKLKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDHVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHGWVCDQRVMKFHKYEEEEDVETGASQDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RNMTL1, or RNA N7-methyltransferase 1-like protein, is a member of the RNA methyltransferase family, which plays a crucial role in various cellular processes by catalyzing the methylation of RNA molecules. The study of RNMTL1 has gained significance due to its potential involvement in the regulation of gene expression, RNA stability, and cellular signaling pathways. Recent research has suggested that RNMTL1 may be linked to various diseases, including cancers and neurological disorders, where abnormal RNA methylation patterns are observed. Understanding the functional mechanisms and pathways of RNMTL1 could reveal new insights into the molecular basis of these diseases and help identify novel therapeutic targets. The recombinant expression of RNMTL1 protein allows for biochemical studies and functional assays, aiding in the determination of its enzymatic activity and interaction with RNA substrates. Exploring the structure-function relationship of RNMTL1 through recombinant protein studies could also elucidate its role in RNA metabolism and its potential as a biomarker for disease states. Overall, the investigation of RNMTL1 recombinant proteins not only contributes to the fundamental understanding of RNA modification but also opens avenues for innovative research in translational medicine.
