Analytical Data
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Gene name
MRPS36
- Application
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Alternative Names
1110018B13Rik; 28S ribosomal protein S36; DC47; MGC22896; mitochondrial; MRP-S36; MRPS36; OTTHUMP00000222036; RT36_HUMAN; S36mt
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P82909
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Expression Region
1-103 aa
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AA Sequence
MMGSKMASAS RVVQVVKPHT PLIRFPDRRD NPKPNVSEAL RSAGLPSHSS VISQHSKGSK SPDLLMYQGP PDTAEIIKTL PQKYRRKLVS QEEMEFIQRG GPE
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Molecular Weight
11.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPS36, or mitochondrial ribosomal protein S36, plays a crucial role in mitochondrial protein synthesis and is essential for the proper functioning of the mitochondrial ribosome. Given its involvement in mitochondrial biogenesis and function, research into MRPS36 has garnered interest, particularly in the context of various diseases, including mitochondrial disorders and certain types of cancer. Mitochondria, often referred to as the powerhouses of the cell, are integral to energy production and regulate cellular metabolism. Dysfunction in mitochondrial proteins like MRPS36 can lead to impaired oxidative phosphorylation and has been linked to various pathologies. Additionally, studies have shown that alterations in mitochondrial dynamics and ribosomal protein expression can influence apoptosis and cell proliferation, which further underscores the significance of MRPS36 in health and disease. Understanding the molecular mechanisms and pathways associated with MRPS36 may provide insights into potential therapeutic targets for conditions arising from mitochondrial dysfunction. Consequently, the focus on the recombinant production of MRPS36 allows researchers to investigate its structure, function, and interactions within the mitochondrial context, paving the way for innovative approaches to mitigate diseases associated with mitochondrial abnormalities. This field of study not only enhances our fundamental knowledge of mitochondrial biology but also contributes to the development of strategies aimed at restoring normal function in affected patients.











