Analytical Data
-
Gene name
SLC22A11
- Application
-
Alternative Names
SLC22A11；OAT4；Solute carrier family 22 member 11
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NSA0
-
Expression Region
1-550aa
-
AA Sequence
MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL
-
Molecular Weight
59.9 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SLC22A11 gene encodes a member of the solute carrier family, specifically belonging to the organic cation and anion transporter family. This transporter is predominantly expressed in the kidney, where it plays a crucial role in the renal handling of various endogenous compounds and therapeutic agents. Abnormalities in the SLC22A11 gene have been associated with several health conditions, including hypertension, chronic kidney disease, and drug metabolism variations, highlighting its significance in pharmacogenomics. Research on SLC22A11 recombinant protein is aimed at elucidating its functional mechanisms, substrate specificity, and physiological roles. By producing and characterizing this recombinant protein, scientists can investigate its interactions with diverse substrates under controlled laboratory conditions, which can provide insights into its transport capabilities and regulatory mechanisms. Additionally, understanding the structure-function relationship of SLC22A11 may assist in developing targeted therapies for related disorders and improving drug safety and efficacy. Overall, the study of SLC22A11 recombinant protein is pivotal for advancing our knowledge of renal transport processes and their implications for human health.
