Analytical Data
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Gene name
MRPS31
- Application
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Alternative Names
28S ribosomal protein S31; 28S ribosomal protein S31; mitochondrial; Imogen 38; IMOGN38; mitochondrial; MRP-S31; MRPS31; RT31_HUMAN; S31mt
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92665
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Expression Region
66-395 aa
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AA Sequence
ICSKK DKQSVRTEET SKETSESQDS EKENTKKDLL GIIKGMKVEL STVNVRTTKP PKRRPLKSLE ATLGRLRRAT EYAPKKRIEP LSPELVAAAS AVADSLPFDK QTTKSELLSQ LQQHEEESRA QRDAKRPKIS FSNIISDMKV ARSATARVRS RPELRIQFDE GYDNYPGQEK TDDLKKRKNI FTGKRLNIFD MMAVTKEAPE TDTSPSLWDV EFAKQLATVN EQPLQNGFEE LIQWTKEGKL WEFPINNEAG FDDDGSEFHE HIFLEKHLES FPKQGPIRHF MELVTCGLSK NPYLSVKQKV EHIEWFRNYF NEKKDILKES NIQFN
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Molecular Weight
45.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPS31, a mitochondrial ribosomal protein, is part of the 28S mitochondrial ribosomal subunit and plays a crucial role in mitochondrial translation, which is essential for proper cellular respiration and energy production. Dysfunction of mitochondrial ribosomes has been implicated in various human diseases, including mitochondrial myopathies and metabolic syndromes. Research into MRPS31, particularly its structure and function, has gained attention due to its potential role in ribosomal biogenesis and mitochondrial protein synthesis. Understanding MRPS31's interactions within the mitochondrial ribosome and its contribution to mitochondrial function can provide insights into the underlying mechanisms of mitochondrial-associated diseases. Furthermore, the exploration of MRPS31 as a biomarker or therapeutic target holds promise for developing novel treatments aimed at correcting mitochondrial dysfunction. Given the increasing recognition of mitochondrial involvement in a range of pathological conditions, MRPS31's study represents a pivotal step toward elucidating the complexities of mitochondrial biology and its impact on human health.
