Analytical Data
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基因名
PPIL3
- Application
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别名
PPIL3;Peptidyl-prolyl cis-trans isomerase-like 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H2H8
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表达区间
1-161aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMSVTLHTDVGDIKIEVFCERTPKTCENFLA LCASNYYNGCIFHRNIKGFMVQTGDPTGTGRGGNSIWGKKFEDEYSEYLK HNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLDE LEKLPVNEKTYRPLNDVHIKDITIHANPFAQ
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分子量
20 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PPIL3, or peptidyl-prolyl isomerase-like 3, is a member of the cyclophilin family of proteins, which are known for their role in catalyzing the cis-trans isomerization of proline residues in polypeptides. This post-translational modification is crucial for protein folding and function, affecting various cellular processes. Recent studies have highlighted the importance of PPIL3 in regulating cellular signaling pathways, particularly those related to inflammation and apoptosis. Research has indicated that PPIL3 may play a role in cancer progression and response to therapies, making it a potential biomarker and therapeutic target. Additionally, understanding PPIL3's structure and function through recombinant protein studies can provide insights into its mechanistic roles in diseases. The development of PPIL3 recombinant proteins allows for detailed biochemical analyses, structure-function studies, and the potential for high-throughput screening for inhibitors, which could lead to novel therapeutic strategies. Overall, the exploration of PPIL3 as a recombinant protein is pivotal for unveiling its biological significance and therapeutic potential in various diseases, particularly in oncology and inflammatory conditions.
