Analytical Data
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基因名
Cd36
- Application
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别名
CD36;GP3B;GP4;Platelet glycoProtein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P16671
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表达区间
31-439aa
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氨基酸序列
DLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNS SNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGT EADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLW GYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTY KGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFE SDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDI SKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFT LQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMF RSQVTGKIN
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分子量
53 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD36 is a class B scavenger receptor that plays a crucial role in various physiological and pathological processes, including lipid metabolism, atherosclerosis, insulin resistance, and inflammation. Its ability to bind to a variety of ligands, such as fatty acids and oxidized low-density lipoproteins (oxLDLs), makes it an essential player in the uptake and transport of lipids in tissues. Given its involvement in metabolic diseases, CD36 has become a target for therapeutic interventions aimed at modulating lipid homeostasis and inflammation. Research on recombinant CD36 proteins has been instrumental in elucidating the structural and functional characteristics of this receptor. By generating CD36 in a recombinant form, scientists can study its ligand-binding properties, signaling pathways, and the modulation of its activity in response to different stimuli. Moreover, CD36's role in macrophage function and its interaction with the immune system highlight its potential as a drug target for atherogenesis and metabolic disorders. Overall, the exploration of CD36 recombinant proteins not only enhances our understanding of lipid metabolism and immune response but also opens avenues for developing novel therapeutic strategies for related diseases.
