Analytical Data
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Gene name
PECAM1
- Application
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Alternative Names
PECAM1;Platelet endothelial cell adhesion molecule
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P16284
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Expression Region
28-601aa
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AA Sequence
QENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYK DDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQVLV EGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKL KREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELV TVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKA IVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSK PELESSFTHLDQGERLNLSCSIPGAPPANFTIQKEDTIVSQTQDFTKIAS KSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTI EVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDNPTEDVEYQCV ADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNE GSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKANKEQEGEYYCTAFNR ANHASSVPRSKILTVRVILAPWKK
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Molecular Weight
91 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PECAM1 (Platelet Endothelial Cell Adhesion Molecule 1), also known as CD31, is a crucial glycoprotein expressed on the surface of endothelial cells and platelets, playing a vital role in various physiological and pathological processes, including immune response, inflammation, and angiogenesis. Its involvement in cell adhesion and migration has garnered interest in the fields of vascular biology and immunology. The study of recombinant PECAM1 proteins has been undertaken to understand better the molecular mechanisms underlying its function and interactions. These recombinant proteins allow researchers to investigate PECAM1’s role in cell-cell adhesion and permeability in vitro, as well as to evaluate its potential as a therapeutic target in diseases characterized by endothelial dysfunction, such as atherosclerosis, diabetes, and cancer. By generating and analyzing PECAM1 recombinant proteins, scientists can explore the structure-function relationships, optimize binding properties, and assess the impact of post-translational modifications on its biological activities. Such research contributes to a broader understanding of endothelial biology and may aid in the development of novel strategies for treating related vascular diseases.
