Analytical Data
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基因名
PHB
- Application
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别名
PHB1;PHB;Prohibitin 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35232
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表达区间
1-272aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV GEGTHFLIPW VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA SQLPRIFTSI GEDYDERVLP SITTEILKSV VARFDAGELI TQRELVSRQV SDDLTERAAT FGLILDDVSL THLTFGKEFT EAVEAKQVAQ QEAERARFVV EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK LEAAEDIAYQ LSRSRNITYL PAGQSVLLQL PQ
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PHB (Prohibitin) is a highly conserved protein that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Recent research has highlighted its involvement in mitochondrial function and cellular signaling pathways, making it an attractive target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders. PHB exists in multiple forms, including cytosolic and mitochondrial localizations, and has been shown to interact with various molecular partners, influencing cell fate decisions. The study of recombinant PHB proteins offers insights into their structure-function relationships and regulatory mechanisms. With advances in recombinant DNA technology, scientists can produce PHB in a controlled environment, facilitating detailed investigations into its biological roles and potential applications in drug development. Understanding the dynamics of PHB through recombinant approaches may pave the way for novel strategies in treating diseases associated with its dysregulation, making it a subject of significant interest in both basic and applied biomedical research.
