Analytical Data
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Gene name
HLA-B
- Application
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Alternative Names
HLA-B；HLAB；HLA class I histocompatibility antigen. B alpha chain
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96DW9
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Expression Region
25-308aa
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AA Sequence
GSHSMRYFYTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQICKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPI
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Molecular Weight
36.8kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HLA-B recombinant proteins are crucial for understanding the human immune response, as they play a significant role in the presentation of antigens to T cells. The Human Leucocyte Antigen (HLA) system, particularly the HLA-B gene, is known for its high polymorphism, which affects individual immune responses to pathogens and is linked to various diseases, including autoimmune disorders and transplant rejection. Research into HLA-B recombinant proteins enables scientists to investigate the structure-function relationships of these proteins, their interaction with other immune components, and their role in disease processes. By producing these proteins in a recombinant system, researchers can study their biological activities, binding affinities to different peptides, and implications for drug development and vaccine design. Furthermore, HLA-B proteins are essential for the study of personalized medicine, as understanding individual variations in HLA-B can lead to tailored therapeutic approaches in immunotherapy and organ transplantation. Overall, the investigation of HLA-B recombinant proteins is vital for advancing our knowledge of immune mechanisms and improving clinical outcomes in various health conditions.
