Analytical Data
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基因名
PTPRA
- Application
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别名
PTPRA;PTPA;PTPRL2;Receptor-type tyrosine-Protein phosphatase alpha
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P18433
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表达区间
20-151aa
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氨基酸序列
NNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGNSDSKDRRDETP
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分子量
15.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTPRA (Protein Tyrosine Phosphatase Receptor Type A) is a member of the protein tyrosine phosphatase family, which plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and signaling pathways. Dysregulation of PTPRA has been implicated in various diseases, particularly cancer, where it may contribute to tumor progression and metastasis. The study of PTPRA recombinant proteins is essential for understanding its structure-function relationships and elucidating the molecular mechanisms behind its activity. Researchers have focused on producing recombinant PTPRA to facilitate in vitro studies that assess its enzymatic functions, interactions with substrates, and potential as a therapeutic target. By generating PTPRA in a controlled environment, scientists can investigate the effects of specific mutations, post-translational modifications, and other factors that influence its activity. Furthermore, understanding PTPRA's role in tumor biology could lead to the development of novel biomarkers and targeted therapies, making it a significant focus of ongoing cancer research. Through the expression and purification of PTPRA recombinant proteins, researchers aim to advance our knowledge of this phosphatase's functions and its implications in health and disease, thereby opening new avenues for therapeutic interventions.












