Analytical Data
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Gene name
PFDN4
- Application
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Alternative Names
PFDN4;PFD4;Prefoldin subunit 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NQP4
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Expression Region
1-134aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MAATMKKAAA EDVNVTFEDQ QKINKFARNT SRITELKEEI EVKKKQLQNL EDACDDIMLA DDDCLMIPYQ IGDVFISHSQ EETQEMLEEA KKNLQEEIDA LESRVESIQR VLADLKVQLY AKFGSNINLE ADES
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Molecular Weight
17 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PFDN4 (Prefoldin 4) is a member of the prefoldin family, which plays a crucial role in the protein folding process by assisting in the proper assembly of multiprotein complexes. Research into PFDN4 has gained momentum due to its association with various biological processes and potential implications in disease. Emerging studies indicate that PFDN4 might be involved in the regulation of protein homeostasis, thereby affecting cellular stress responses and developmental pathways. Moreover, alterations in PFDN4 expression have been linked to several conditions, including cancer and neurodegenerative disorders, highlighting its significance in maintaining cellular integrity. Investigating the recombinant expression of PFDN4 facilitates a deeper understanding of its functional roles and interactions within the cellular environment. Utilizing recombinant protein technologies allows researchers to produce PFDN4 in a controlled manner, enabling detailed studies of its structure, dynamics, and biological activity. This research is not only vital for elucidating the molecular mechanisms underlying PFDN4's functions but also holds promise for therapeutic advancements by identifying potential drug targets or biomarkers for diseases associated with protein misfolding and aggregation. Consequently, the study of recombinant PFDN4 presents a pivotal avenue for innovation in both basic biology and clinical applications, making it a significant focus in contemporary biomedical research.
