Analytical Data
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基因名
OXSR1
- Application
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别名
OXSR1;KIAA1101;OSR1;Serine/threonine-Protein kinase OSR1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95747
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表达区间
1-527aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMSEDSSALPWSINRDDYELQEVIGSGA TAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVS YYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATIL REVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDI TRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPY HKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPE KRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGR LHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDP VGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGS QETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGR DLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
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分子量
60 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Identification
Protein Description
OXSR1, or oxidative stress-responsive kinase 1, is a serine/threonine protein kinase that plays a crucial role in cellular responses to oxidative stress and maintains cellular homeostasis. Research has shown that OXSR1 is involved in various physiological processes, including regulating ion transport, cell proliferation, and apoptosis under stress conditions. Its activity is linked to key signaling pathways that respond to environmental stressors, making it a significant protein in understanding cellular adaptations that can influence diseases such as cancer and neurodegenerative disorders. In recent years, scientists have focused on characterizing the structure and function of the OXSR1 protein, particularly its kinase domain, to uncover mechanisms of action and potential therapeutic targets. The production of recombinant OXSR1 proteins has facilitated biochemical studies and functional assays, providing insights into the protein’s role in mediating cellular responses to oxidative stress. Additionally, understanding the interactions between OXSR1 and its substrates has important implications for developing strategies to modulate its activity in disease contexts. Overall, the ongoing research on OXSR1 is vital for uncovering its contributions to cellular signaling networks and developing novel therapeutic approaches for stress-related diseases.
