Analytical Data
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基因名
Cmklr2
- Application
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别名
Cmklr2；GPR1；Chemerin-like receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P46090
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表达区间
1-353aa
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氨基酸序列
MEVSREMLFEELDNYSYALEYYSQEPDAEENVYPGIVHWISLLLYALAFVLGIPGNAIVIWFMGFKWKKTVTTLWFLNLAIADFVFVLFLPLYISYVALSFHWPFGRWLCKLNSFIAQLNMFSSVFFLTVISLDRYIHLIHPGLSHPHRTLKNSLLVVLFVWLLASLLGGPTLYFRDTVEVNNRIICYNNFQEYELTLMRHHVLTWVKFLFGYLLPLLTMSSCYLCLIFKTKKQNILISSKHLWMILSVVIAFMVCWTPFHLFSIWELSIHHNSSFQNVLQGGIPLSTGLAFLNSCLNPILYVLISKKFQARFRASVAEVLKRSLWEASCSGTVSEQLRSAETKSLSLLETAQ
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分子量
42.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Cmklr2 (Chemokine-like receptor 2) is a G-protein-coupled receptor implicated in various physiological and pathological processes, including immune response, inflammation, and possibly tumor progression. Its study has gained attention due to its potential role in mediating chemokine signaling pathways, which are crucial for leukocyte migration and tissue homeostasis. Research indicates that Cmklr2 may interact with specific ligands, leading to an array of cellular responses that can influence immune cell activation and trafficking. The significance of Cmklr2 in the context of inflammatory diseases and cancer promotes the exploration of its structure and function through recombinant protein technologies. By producing and characterizing Cmklr2 recombinant proteins, researchers can elucidate its binding properties, signaling mechanisms, and developmental roles, laying the groundwork for therapeutic interventions targeting this receptor. Understanding Cmklr2's function at the molecular level not only enhances our knowledge of chemokine signaling but also opens avenues for novel biomarker and drug development in various disease states.
