Cat: PA1000-2261

Recombinant Human OTOR Protein,His

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Analytical Data

  • Gene name

    OTOR

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    OTOR;FDP;MIAL;Otoraplin

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NRC9

  • Expression Region

    18-128aa

  • AA Sequence

    VHG IFMDRLASKK LCADDECVYT ISLASAQEDY NAPDCRFINV KKGQQIYVYS KLVKENGAGE FWAGSVYGDG QDEMGVVGYF PRNLVKEQRV YQEATKEVPT TDIDFFCE

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

OTOR (Osteoactivin, also known as OC/OTOR) is a protein that has garnered significant attention in recent years due to its involvement in various physiological processes, including bone metabolism, immune responses, and tissue repair. Initial studies indicated that OTOR is expressed in osteoblasts and osteoclasts, leading researchers to explore its role in bone homeostasis and potential implications for osteoporosis and other bone-related disorders. Furthermore, OTOR has been implicated in inflammatory processes and may play a critical role in modulating immune responses, making it a potential target for therapeutic interventions in autoimmune diseases and inflammation-related conditions. Advances in molecular biology techniques have enabled scientists to investigate the mechanisms of OTOR more comprehensively, revealing its complex interactions with signaling pathways involved in cell proliferation and differentiation. Given the increasing prevalence of diseases associated with bone and immune systems, the research on OTOR is crucial for developing novel therapeutic strategies. Understanding its structure, function, and regulatory mechanisms could provide valuable insights into disease pathology and lead to the identification of new biomarkers for diagnosis and treatment efficacy. Overall, OTOR represents a promising area of research, bridging molecular biology with clinical applications, and holds the potential to contribute significantly to our understanding of bone health and immunological functions.

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