Analytical Data
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基因名
NSL1
- Application
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别名
NSL1;C1orf48;Kinetochore-associated Protein NSL1 homolog
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96IY1
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表达区间
1-281aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAGSPEL VVLDPPWDKE LAAGTESQAL VSATPREDFR VRCTSKRAVT EMLQLCGRFV QKLGDALPEE IREPALRDAQ WTFESAVQEN ISINGQAWQE ASDNCFMDSD IKVLEDQFDE IIVDIATKRK QYPRKILECV IKTIKAKQEI LKQYHPVVHP LDLKYDPDPA PHMENLKCRG ETVAKEISEA MKSLPALIEQ GEGFSQVLRM QPVIHLQRIH QEVFSSCHRK PDAKPENFIT QIETTPTETA SRKTSDMVLK RKQTKDCPQR KWYPLRPKKI NLDT
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The NSL1 protein is a crucial component of the NSL complex, which plays a significant role in the regulation of gene expression and chromatin modification. Researchers have focused on NSL1 due to its implications in maintaining genome integrity and its involvement in various cellular processes, including transcriptional activation and chromatin remodeling. NSL1 is essential for the regulation of developmental and differentiation processes, as it interacts with other chromatin-associated proteins to modulate the accessibility of DNA for transcription machinery. Dysregulation of NSL1 has been linked to several diseases, including cancer and developmental disorders, making it a focal point for understanding the molecular mechanisms underlying these conditions. Recent studies have employed advanced techniques such as CRISPR/Cas9 gene editing, RNA sequencing, and mass spectrometry to elucidate the functional roles of NSL1 and its interactions within the chromatin landscape. These investigations are pivotal in uncovering how NSL1 contributes to broader epigenetic regulatory networks and may provide insights into potential therapeutic targets for diseases associated with chromatin dysregulation. As such, the research on NSL1 not only enhances our understanding of fundamental genetic processes but also paves the way for novel approaches in biomedical research and therapeutic development.
