Analytical Data
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基因名
NHLH1
- Application
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别名
NHLH1;BHLHA35;HEN1;Helix-loop-helix Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q02575
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表达区间
1-133aa
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氨基酸序列
MMLNSDTMEL DLPPTHSETE SGFSDCGGGA GPDGAGPGGP GGGQARGPEP GEPGRKDLQH LSREERRRRR RATAKYRTAH ATRERIRVEA FNLAFAELRK LLPTLPPDKK LSKIEILRLA ICYISYLNHV LDV
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NHLH1 (Nuclear Hormone Receptor-Related Protein 1) is a member of the basic helix-loop-helix (bHLH) transcription factor family, playing a crucial role in various physiological processes, including neurogenesis, cell differentiation, and metabolism. The interest in NHLH1 has surged due to its involvement in key regulatory pathways that are essential for the development and function of the central nervous system and its potential implications in metabolic disorders. Recent studies suggest that NHLH1 may influence the expression of genes related to energy homeostasis and insulin signaling, making it a potential target for therapeutic interventions in obesity and diabetes. Understanding the structure and function of NHLH1 through recombinant protein studies is vital for elucidating its mechanisms of action. By producing NHLH1 as a recombinant protein, researchers can investigate its binding affinities to DNA, protein-protein interactions, and post-translational modifications, thereby gaining insights into its role in gene regulation. Furthermore, studying NHLH1 in various model systems can help clarify its contributions to health and disease, with the ultimate goal of identifying novel strategies for the treatment of metabolic and neurological disorders. Thus, the exploration of NHLH1 as a recombinant protein remains a promising avenue in the field of molecular biology and translational medicine.
