Analytical Data
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基因名
NEURL2
- Application
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别名
NEURL2;C20orf163;Neuralized-like Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BR09
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表达区间
1-285aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMAAASEPVDSGALWGLERPEPPPTRFH RVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGW CGHLRLGLTALDPASLAPVPEFSLPDLVNLGHTWVFAITRHHNRVPREGR PEAEAAAPSRPPTLLVEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYE LNVLPPTARRSRLGVLFCPRPDGTADMHIIINGEDMGPSARGLPAAQPLY AVVDVFASTKSVRLVQLEYGLPSLQTLCRLVIQRSMVHRLAIDGLHLPKE LKDFCKYE
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NEURL2 (Neural Renin-angiotensin System Component 2) is a gene that encodes a member of the E3 ubiquitin ligase family, which plays a crucial role in protein degradation and regulation of various cellular processes. Its involvement in neural development and potential link to neurodegenerative diseases has garnered increasing attention from researchers. Studies suggest that NEURL2 may influence neuronal survival, synaptic function, and response to stress, making it a significant candidate for understanding the underlying mechanisms of neurodegenerative disorders like Alzheimer's and Parkinson's disease. Given its role in ubiquitination, NEURL2 might contribute to the maintenance of protein homeostasis in neurons, and its dysregulation could lead to the accumulation of misfolded proteins, a hallmark of many neurodegenerative conditions. Current research efforts are focused on characterizing the structure and function of NEURL2 recombinant proteins, exploring their interactions with other cellular proteins, and elucidating their roles in neuronal stress response pathways. Understanding NEURL2 through recombinant protein studies can provide insights into its potential as a therapeutic target and enhance our knowledge of the molecular pathology of neurodegeneration. Overall, the investigation of NEURL2 holds promise for unveiling novel strategies aimed at mitigating the effects of neurodegenerative diseases and improving neurological health.
