Analytical Data
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基因名
COL4a2
- Application
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别名
COL4a2；Collagen alpha-2(IV) chain
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P08572
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表达区间
1493-1712aa
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氨基酸序列
VKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSV CEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVS PGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADT LKAGLIRTHISRCQVCMKNL
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分子量
168 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
COL4A2, a member of the collagen family, encodes alpha-2 chain of type IV collagen, which is crucial for the structural integrity of basement membranes. Abnormalities in the COL4A2 gene have been linked to various human diseases, including nephropathy, Alport syndrome, and connective tissue disorders. Research on COL4A2 recombinant proteins is essential for understanding the molecular mechanisms underlying these diseases and developing potential therapeutic strategies. The production of COL4A2 recombinant proteins allows for detailed studies of its structural properties, interactions with other extracellular matrix components, and its role in cell signaling pathways. Moreover, COL4A2 recombinant proteins can be utilized in tissue engineering and regenerative medicine, offering insights into their potential applications in repairing or regenerating damaged tissues. As a result, the study of COL4A2 and its recombinant forms contributes significantly to the knowledge of collagen-related pathologies and advances in biomedical research.
