Analytical Data
-
基因名
MYL12B
- Application
-
别名
DAPK3;ZIPK;Death-associated Protein kinase 3
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O14950
-
表达区间
1-172aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMSSKKA KTKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DAYLDAMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEATG TIQEDYLREL LTTMGDRFTD EEVDELYREA PIDKKGNFNY IEFTRILKHG AKDKDD
-
分子量
22 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MYL12B, also known as myosin light chain 12B, is a crucial protein encoded by the MYL12B gene and plays a significant role in the regulation of smooth muscle contraction and various cellular processes, such as cell migration and shape maintenance. The protein is a part of the myosin-II complex, which is essential for muscle contraction and cellular motility. Recent studies have highlighted the importance of MYL12B in various physiological and pathological contexts, including its involvement in cancer cell invasion, metastasis, and the modulation of inflammatory responses. Researchers are increasingly interested in the functional implications of MYL12B in both normal and diseased states, particularly its post-translational modifications and interactions with other cellular components. Additionally, the reconstitution of MYL12B as a recombinant protein enables detailed structural and functional studies, paving the way for potential therapeutic applications aimed at targeted modulation of its activity. Understanding the intricate roles of MYL12B could provide valuable insights into relevant biological pathways and contribute to the development of novel strategies for treating diseases characterized by aberrant cell behavior, including cancer and cardiovascular disorders. Thus, the study of MYL12B and its recombined forms is of great importance in the fields of molecular biology, pharmacology, and medical research, highlighting the need for continued investigation into its mechanisms and potential interventions.
