Analytical Data
-
基因名
MSRA
- Application
-
别名
MSRA;Mitochondrial peptide methionine sulfoxide reductase
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9UJ68
-
表达区间
24-235aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMGNSAS NIVSPQEALP GRKEQTPVAA KHHVNGNRTV EPFPEGTQMA VFGMGCFWGA ERKFWVLKGV YSTQVGFAGG YTSNPTYKEV CSEKTGHAEV VRVVYQPEHM SFEELLKVFW ENHDPTQGMR QGNDHGTQYR SAIYPTSAKQ MEAALSSKEN YQKVLSEHGF GPITTDIREG QTFYYAEDYH QQYLSKNPNG YCGLGGTGVS CPVGIKK
-
分子量
26 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research background of MSRA (Methionine Sulfoxide Reductase A) recombinant proteins centers on their crucial role in cellular defense mechanisms against oxidative stress. MSRA is an enzyme that catalyzes the reduction of methionine sulfoxide (MetSO) back to methionine, a process vital for maintaining cellular redox balance and protein function. Elevated levels of oxidative stress are linked to various diseases, including neurodegenerative disorders, cardiovascular diseases, and aging. Thus, understanding the function and mechanisms of MSRA can provide insights into how cells mitigate oxidative damage. Recombinant forms of MSRA allow researchers to elucidate the enzyme's structure-function relationships, assess its activity under different physiological conditions, and explore its potential therapeutic applications. Moreover, studying MSRA in various model organisms can enhance our grasp of its evolutionary conservation and functional importance across different biological systems. The reengineering of MSRA for enhanced stability and activity also holds promise for developing novel antioxidant therapies, thereby contributing to advancements in biotechnology and medicine aimed at combating oxidative stress-related diseases. Overall, the investigation into MSRA recombinant proteins underpins a vital area of research in oxidative stress biology, with implications for health and disease management.
