Analytical Data
-
基因名
MSI2
- Application
-
别名
MSI2;RNA-binding Protein Musashi homolog 2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q96DH6
-
表达区间
1-328aa
-
氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMEANGSQGTSGSANDSQHDPGKMFIGG LSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDK VLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVK QYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINN KMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYG RGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGAN SPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGY H
-
分子量
38 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MSI2, or Musashi RNA-binding protein 2, is a member of the Musashi family of RNA-binding proteins that play crucial roles in the regulation of stem cell biology, cellular differentiation, and oncogenesis. It has been identified as an important player in maintaining the properties of stem cells and is often found to be dysregulated in various cancers, contributing to tumorigenesis and cancer progression. The research surrounding MSI2 largely focuses on its mechanisms of action, particularly its role in post-transcriptional regulation of target mRNAs, which can affect cell fate decisions and the proliferation of cancer cells. Studies have shown that MSI2 can interact with specific RNA sequences, modulating the stability and translation of its target mRNAs, thereby influencing critical signaling pathways involved in cell cycle regulation and apoptosis. Given its association with cancer, MSI2 has emerged as a potential biomarker for tumor progression and a target for novel therapeutic strategies. As researchers continue to elucidate the functional roles of MSI2 in different biological contexts, particularly in malignancies, understanding the molecular pathways mediated by MSI2 could pave the way for innovative approaches in cancer treatment and regenerative medicine. Therefore, the characterization of recombinant MSI2 protein becomes fundamental in studying its structure-function relationships, exploring its binding properties, and identifying potential inhibitors or modulators, all of which could significantly advance our understanding of its contribution to both normal physiology and disease states.












