Analytical Data
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基因名
LCE1D
- Application
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别名
LCE1D; LEP4Late cornified envelope protein 1D; Late envelope protein 4
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T752
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表达区间
1-114aa
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氨基酸序列
MSCQQSQQQCQPPPKCTPKCTPKCPAPKCPPKCPPVSSCCSVSSGGCCGSSSGGGCGSNSGGCCSSGGGGCCLSHHRRHRSHRRRPQSSDCCSQPSGGSSCCGGGSSQHSGGCC
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分子量
12.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LCE1D, a member of the late cornified envelope (LCE) family of proteins, is primarily expressed in the epidermis and plays a crucial role in skin barrier function and the regulation of keratinocyte differentiation. Research on LCE1D has gained interest due to its potential involvement in various dermatological conditions and its association with skin diseases such as psoriasis and atopic dermatitis. The protein is hypothesized to contribute to the structural integrity and water retention of the skin, which are essential for maintaining overall skin health. Advances in proteomics and genomics have allowed for a more in-depth understanding of LCE1D's expression patterns and regulatory mechanisms. Studies indicate that LCE1D may participate in inflammatory responses and cellular signaling pathways that govern keratinocyte behavior. Additionally, given the rising incidence of skin-related disorders, exploring LCE1D's functional role could lead to novel therapeutic strategies for enhancing skin repair and barrier recovery. Understanding the precise mechanisms of LCE1D function and regulation may also provide insights into the development of targeted treatments for skin pathologies, making it an important focal point for ongoing research in dermatology and molecular medicine.
