Analytical Data
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基因名
KRTAP4-4
- Application
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别名
KRTAP4-4; KAP4.13; KAP4.4; KRTAP4-13; KRTAP4.13; KRTAP4.4Keratin-associated protein 4-4; Keratin-associated protein 4-13; Keratin-associated protein 4.13
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYR3
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表达区间
1-166aa
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氨基酸序列
MVNSCCGSVCSDQGCGLENCCRPSYCQTTCCRTTCCRPSCCVSSCCRPQCCQTTCCRTTCCHPSCCVSSCCRPQCCQSVCCQPTCCRPQCCQTTCCRTTCCRPSCCRPQCCQSVCCQPTCCCPSYCVSSCCRPQCCQTTCCRTTCCRPSCCVSRCYRPHCGQSLCC
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分子量
44.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRTAP4-4 (Keratin Associated Protein 4-4) is a member of the keratin-associated protein (KAP) family, which plays a crucial role in the structure and function of the hair, skin, and nails by influencing the properties of keratin fibers. Recent studies have highlighted the significance of KRTAP4-4 in the formation of the hair shaft, contributing to its mechanical strength and resilience. Mutations or alterations in KRTAP4-4 gene expression can lead to various hair disorders, making it an important target for research in dermatology and genetics. Additionally, KRTAP4-4 serves as a valuable model for studying the molecular mechanisms of keratinization and the interplay between different keratin-associated proteins in epithelial tissues. Understanding the structure and function of recombinant KRTAP4-4 protein could facilitate advancements in regenerative medicine, cosmetic science, and the development of therapeutic strategies for hair and skin disorders. Researchers aim to elucidate its properties, interactions, and potential applications, paving the way for novel treatments and improving the understanding of keratin biology at both the basic and clinical levels.
