Analytical Data
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Gene name
MAFG
- Application
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Alternative Names
MAFG;Transcription factor MafG
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15525
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Expression Region
1-162aa
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AA Sequence
MTTPNKGNKA LKVKREPGEN GTSLTDEELV TMSVRELNQH LRGLSKEEIV QLKQRRRTLK NRGYAASCRV KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART VARSPVAPAR GPLAAGLGPL VPGKVAATSV ITIVKSKTDA RS
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Molecular Weight
20 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAFG (Maf G proto-oncogene) is a member of the basic leucine zipper (bZIP) transcription factor family and has garnered interest due to its role in regulating various biological processes, including cell differentiation, apoptosis, and responses to oxidative stress. Research suggests that MAFG is involved in the transcriptional regulation of genes related to metabolic pathways and has been implicated in the pathogenesis of several diseases, notably cancer and cardiovascular conditions. The protein is understood to interact with other transcription factors and co-regulators, influencing gene expression in response to physiological and pathological stimuli. Recent studies have focused on the potential of MAFG as a biomarker for disease progression and as a therapeutic target, given its significant role in cellular responses to environmental changes. Understanding the structure and function of MAFG through the study of recombinant proteins could illuminate the molecular mechanisms of its action, paving the way for novel therapeutic strategies. Consequently, the recombinant expression and characterization of MAFG provide essential insights into its functional roles, interactions, and potential applications in medicine. Researchers are actively investigating the modular domains of MAFG, exploring how its reconstitution may benefit the development of small molecule inhibitors that could modulate its activity in disease contexts.
