Analytical Data
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Gene name
INHBA
- Application
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Alternative Names
INHBA;Inhibin beta A chain
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P08476
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Expression Region
311-426aa
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AA Sequence
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
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Molecular Weight
16.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
INHBA, or inhibin beta A, is a member of the transforming growth factor-beta (TGF-β) superfamily, playing a crucial role in various biological processes, including reproductive function, embryonic development, and cellular differentiation. Its protein product, activin A, regulates several physiological functions by influencing the growth and differentiation of various cell types, particularly in the reproductive system. Research into recombinant INHBA proteins has gained significant traction due to their potential therapeutic applications, particularly in treating infertility and developmental disorders. Moreover, alterations in INHBA expression have been implicated in various pathologies, including certain cancers, where it can act as a tumor promoter or suppressor depending on the context. The development of recombinant INHBA proteins has enabled researchers to delve deeper into its functional mechanisms, investigate its role in disease progression, and explore its application in regenerative medicine. This includes harnessing its signaling pathways for therapeutic interventions aimed at enhancing tissue repair and modulating immune responses. Overall, the study of recombinant INHBA proteins is pivotal for understanding hormone regulation, developing biomarkers for specific diseases, and advancing novel treatment strategies.
