Analytical Data
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基因名
ING1
- Application
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别名
ING1;Inhibitor of growth Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UK53-2
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表达区间
1-279aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGS MLSPANG EQ LHLVNYVE DYLDSIESLP FDLQRNVSLM REIDAKYQEI LKELDECYER FSRETDGAQK RR MLHCVQRA LIRSQELGDE KIQIVSQMVE LVENRTRQVD SHVELFEAQQ ELGDTAGNSG KA GADRPKGE AAAQADKPNS KRSRRQRNNE NRENASSNHD HDDGASGTPK EKKAKTSKKK KR SKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD NDECPIEWFH FSCVGLNHKP KG KWYCPKCR GENEKTMDKA LEKSKKERAY NR
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of ING1 (Inhibitor of Growth Protein 1) recombinant protein has gained significant attention in the field of cancer research due to its critical role as a tumor suppressor. ING1 is known to participate in various cellular processes, including cell cycle regulation, apoptosis, and DNA repair. Its ability to interact with various chromatin remodeling complexes underscores its importance in transcriptional regulation and maintaining genomic stability. Emerging evidence suggests that altered expression or mutations in ING1 may contribute to tumorigenesis and cancer progression, making it a potential biomarker for diagnosing and monitoring certain malignancies. Researchers have focused on producing recombinant forms of ING1 to facilitate in vitro studies, elucidating its mechanisms of action, interaction with other proteins, and potential therapeutic applications. By understanding ING1's function and pathways, scientists aim to identify novel strategies for targeted cancer therapies, enhancing patient outcomes and paving the way for innovative treatment modalities. The exploration of ING1 recombinant protein thus represents a pivotal area of research with implications for cancer biology and therapeutic interventions.
