Analytical Data
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Gene name
KCNIP1
- Application
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Alternative Names
A type potassium channel modulatory protein 1; A-type potassium channel modulatory protein 1; KChIP1; KCIP1_HUMAN; Kcnip1; Kv channel interacting protein 1; Kv channel-interacting protein 1; MGC9; MGC95; Potassium channel interacting protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZI2
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Expression Region
1-227aa
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AA Sequence
MGAVMGTFSS LQTKQRRPSK DIAWWYYQYQ RDKIEDELEM TMVCHRPEGL EQLEAQTNFT KRELQVLYRG FKNECPSGVV NEDTFKQIYA QFFPHGDAST YAHYLFNAFD TTQTGSVKFE DFVTALSILL RGTVHEKLRW TFNLYDINKD GYINKEEMMD IVKAIYDMMG KYTYPVLKED TPRQHVDVFF QKMDKNKDGI VTLDEFLESC QEDDNIMRSL QLFQNVM
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Molecular Weight
26.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KCNIP1, also known as K+ channel interacting protein 1, is a member of the K+ channel interacting protein family, which plays a crucial role in the modulation of potassium channels and neuronal excitability. Research has highlighted its involvement in various physiological processes, including synaptic transmission and neuronal development. Additionally, KCNIP1 has been associated with several neurological disorders, such as epilepsy, schizophrenia, and mood disorders, indicating its potential as a therapeutic target. Due to its critical functions in the nervous system, the production and characterization of recombinant KCNIP1 protein have become a focal point in neuroscience research. The recombinant protein can be utilized to investigate its interactions with ion channels and other cellular proteins, enabling researchers to elucidate the molecular mechanisms underlying its role in neuronal function. Understanding KCNIP1's structure and function can provide insights into its regulatory mechanisms and help identify potential intervention points for treating related pathologies. Overall, the study of KCNIP1 recombinant protein is essential for advancing our comprehension of synaptic biology and developing targeted therapeutics for neuropsychiatric disorders.
